Preheat oven to 400 degrees.
In a large skillet, brown ground beef and cook onion. Make sure you drain the grease fully from the skillet and cook onion until it is soft.
Spray a 9 inch pie pan with cooking spray, or grease it with butter.
Add Ground Beef and Onion to the Pie Pan.
Add Cheese over this mixture.
In a large or medium bowl, mix together salt, pepper, garlic powder, eggs, milk and Bisquick. Pour this mixture into Pie Pan.
Bake in the oven for 25 minutes.
Make sure you really drain the grease out of the skillet after you have browned the beef. You REALLY don't want this recipe to turn out too greasy.
Don't be afraid to try out different types of cheese! Add some spice with a Mexican blend of cheese, or sprinkle in some swiss cheese for a different taste.
This is one of those great "base recipes" that you can add things to if you'd like. Try adding some bell peppers, Ro-Tel Tomatoes, Corn, Bacon or sub an Onion Soup Mix for the dry spices.